Hydrochloric Acid → HCID 13784605, compound

HRID 569093Notes

Reaction equation

HRID 569093 reaction equation
C([O:3][C:4](=[O:22])[CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:18]=1[O:17][C:16](=[O:19])[C:15]([C:20]#[N:21])=[CH:14]2)C.[OH-].[Na+].Cl>C(O)C>[C:20]([C:15]1[C:16](=[O:19])[O:17][C:18]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][C:9]=2[O:8][CH2:7][CH2:6][CH2:5][C:4]([OH:22])=[O:3])#[N:21]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 54416135HCID 54416135, compound

Product 1

HCID 13784605HCID 13784605, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

After 10 ml of ethanol was added to 6.0 g of 4-(3-cyano-2-oxo-8-chromenyloxy)butyric acid ethyl ester, 50 ml of 2N aqueous solution of sodium hydroxide was added to the mixture and the resultant was stirred for 5 minutes at room temperature. Then the reaction mixture was poured into a mixture of 10 ml of concentrated hydrochloric acid and 200 ml of ice water and a precipitate was filtered, which was recrystallized to give a desired compound.

Workup

  1. additionwas added to the mixture
  2. filtrationa precipitate was filtered
  3. customwhich was recrystallized

Sources & evidence

ORD record
ord-271d9542ee0c48c3acc91f7984feb0bd
Source dataset
uspto-grants-1988_03
Patent number
US04731375

Reaction notes

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