反应详情

95 g (0.388 Mol) of 4-(phthalimido)cyclohexanol are dissolved in 600 ml of chloroform and, after the addition of 450 ml of water and 120 ml of sulfuric acid, 90 g (0.3 Mol) of potassium dichromate are added in batches. The internal temperature of the mixture is maintained at between 25° and 30° C. by slight cooling. The mixture is stirred for a further 3 hours, then the chloroform phase is separated of and the mixture extracted twice more with chloroform. After drying and concentration of the extracts 82 g (86.9% of theory) are obtained.

1. additionare added in batches
2. temperatureThe internal temperature of the mixture is maintained at between 25° and 30° C. by slight cooling
3. customthe chloroform phase is separated of and the mixture
4. extractionextracted twice more with chloroform
5. customAfter drying
6. customconcentration of the extracts 82 g (86.9% of theory) are obtained