Sodium Bicarbonate → HCID 86742046, compound

HRID 569311Notes

Reaction equation

HRID 569311 reaction equation
[Cl:1][CH2:2][CH2:3][C:4]12[CH2:16][CH2:15][C:14](=[O:17])[CH:13]=[C:12]1[C:11]1[C:6](=[CH:7][C:8]([O:20][CH2:21][C:22]([OH:24])=[O:23])=[C:9]([Cl:19])[C:10]=1[Cl:18])[CH2:5]2.C(=O)(O)[O-].[Na+:29]>O>[Cl:1][CH2:2][CH2:3][C:4]12[CH2:16][CH2:15][C:14](=[O:17])[CH:13]=[C:12]1[C:11]1[C:6](=[CH:7][C:8]([O:20][CH2:21][C:22]([O-:24])=[O:23])=[C:9]([Cl:19])[C:10]=1[Cl:18])[CH2:5]2.[Na+:29]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 20148930HCID 20148930, compound

Product 1

HCID 86742046HCID 86742046, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

{[9a-(2-Chloroethyl)-5,6-dichloro-3-oxo-2,3,9,9a-tetrahydro-1H-fluoren-7-yl]oxy}acetic acid (500 mg) is dissolved by stirring and warming with 0.25N sodium bicarbonate solution (5.4 ml). The solution is diluted to 10 ml and sterilized by filtration. All the water that is used in the preparation is pyrogen-free. The concentration of the active agent in the final solution is 5%.

Workup

  1. additionThe solution is diluted to 10 ml and sterilized by filtration

Sources & evidence

ORD record
ord-62360fab674544839110f158219ceed7
Source dataset
uspto-grants-1988_03
Patent number
US04731471

Reaction notes

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