反应详情

温度

-10 °C

A mixture of 7.1 g of 3-methyl-4-pyridylmethylamine, 6.25 g of 2,3,4-pentanetrione, 3-oxime and 125 ml of acetonitrile was stirred at reflux temperature for 5 hours, then cooled at -10° C. The resulting precipitate was collected, washed with cold acetonitrile, dried and then recrystallized from a mixture of chloroform and hexane, giving 4.5 g of the desired compound, mp 185°-187° C.

1. temperatureat reflux temperature for 5 hours
2. customThe resulting precipitate was collected
3. washwashed with cold acetonitrile
4. customdried
5. customrecrystallized from a mixture of chloroform and hexane