HCID 14099741, compound → HCID 14099743, compound

Participants

Reaction Steps

A mixture of 1.5 g of 2-[4-(4-fluorophenyl)-1-piperazinyl]-1-[5-methyl-2-(3-pyridinyl)-1H-imidazol-4-yl]ethanone in 20 ml of dry tetrahydrofuran and 10 ml of 1.7M phenyl magnesium bromide in 10 ml of ether was reacted as described in Example 41 giving 2 g of a foam. This foam was purified by chromatography, giving 0.75 g of the desired product as a light yellow foam.

Provenance & Evidence