Diethyl Ether → HCID 178419722, compound

HRID 569497Notes

Reaction equation

HRID 569497 reaction equation
[N+:1]([NH:4][CH2:5][CH2:6][CH2:7][CH2:8][NH:9][C:10](=[NH:12])[NH2:11])([O-:3])=[O:2].CCOCC.[BrH:18].C(O)(=O)C>>[BrH:18].[N+:1]([NH:4][CH2:5][CH2:6][CH2:7][CH2:8][NH:9][C:10](=[NH:11])[NH2:12])([O-:3])=[O:2]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 21893785Acetic Acid Mixture with Hydrobromic AcidHCID 178512966HCID 178512966, compound

Product 1

HCID 178419722HCID 178419722, compound

Procedure

The compound (3) (112 mg) obtained in Example 6 was dissolved in 1 ml of a 25% HBr/acetic acid solution and the mixture was stirred at room temperature for 30 minutes. To this reaction mixture was added ether to give a precipitate and supernatant was decanted twice. The residue was recrystallized from methanol-ether and collected by filtration. The product was washed with cold methanol-ether to give a white solid.

Workup

  1. customto give a precipitate and supernatant
  2. customwas decanted twice
  3. customThe residue was recrystallized from methanol-ether
  4. filtrationcollected by filtration
  5. washThe product was washed with cold methanol-ether
  6. customto give a white solid

Sources & evidence

ORD record
ord-2a77c923e4df4971b01a04af9a31d1df
Source dataset
uspto-grants-1988_03
Patent number
US04732910

Reaction notes

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