HRID569532

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8259

2,2,2-Trichloroethanol

C2H3Cl3O

HCID9837437

(S)-2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile

C14H11NO2

$结构：CC1(C)[C@H](C(=O)O[C@H](C#N)c2cccc(Oc3ccccc3)c2)[C@@H]1/C=C\C(=O)O$

HCID13093798

未命名化合物

PRODUCTS

生成物

$结构：CC1(C)[C@H](C(=O)O[C@H](C#N)c2cccc(Oc3ccccc3)c2)[C@@H]1/C=C\C(=O)OCC(Cl)(Cl)Cl$

HCID131714333

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

Using the procedure of Step F of Example 9, the ester of Step A after reaction with 2,2,2-trichloroethanol and (S)α-cyano-3-phenoxy-benzyl alcohol was reacted to obtain (S)α-cyano-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2,2-trichloroethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+42.5°±2° (c=0.5% in benzene).

WORKUP

后处理

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