HRID56954

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C(=O)Nc1ccc(-c2cc(=O)[nH]n2C(=O)OC(C)(C)C)cc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O

HCID117622739

未命名化合物

PRODUCTS

生成物

结构：CC(C(=O)Nc1ccc(-c2cc(=O)[nH][nH]2)cc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O

HCID117622742

未命名化合物

PROCEDURE

实验过程

110 mg (0.20 mmol) of tert-butyl 5-[4-({2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-1-carboxylate (racemate) (Example 2.3A) were hydrolysed with TFA according to General Method 2. Yield: 24 mg (27% of theory)