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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 569562Generated: October 27, 2026

Formaldehyde → 7-Pyrrolidinohept-5-ynylamine

https://huagongshe.com/reaction/569562

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantPyrrolidineHCID 31268—
ReactantN-(5-Hexynyl)phthalimideHCID 3346053—
Product7-Pyrrolidinohept-5-ynylamineHCID 20147644—

Reaction Steps

In a manner similar to Description 1 (iii) and (iv), reaction of N-5-hexynylphthalimide, paraformaldehyde and pyrrolidine, followed by treatment with hydrazine hydrate gives 7-pyrrolidinohept-5-ynylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04732980
Source datasetuspto-grants-1988_03
ORD IDord-3ea819fb41bb45e7893ba1bb36c59fb8
Source noteuspto-grants-1988_03