HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → Dichloromethyl 3-(phthalimido)-propyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | 3-(Phthalimido)-propyl formate | HCID 20147862 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Dichloromethyl 3-(phthalimido)-propyl ether | HCID 20147865 | — |
Reaction Steps
A mixture of 3-(phthalimido)-propyl formate (17 g), phosphorus pentachloride (15.2 g) and alcoholfree chloroform was heated for 1 hour on the steam bath. After cooling and addition of ether, the crystalline product was isolated by filtration. M.p. 101°-103° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04732998 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-3d6dd83158044bbdba8879891551f7cb |
| Source note | uspto-grants-1988_03 |