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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 569618Generated: October 30, 2026

Tetraethyl (1-phenoxypropylidene)-bisphosphonate → (1-Phenoxypropylidene)-bisphosphonic acid

https://huagongshe.com/reaction/569618

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetraethyl (1-phenoxypropylidene)-bisphosphonateHCID 53742288—
SolventBromotrimethylsilaneHCID 76113—
Product(1-Phenoxypropylidene)-bisphosphonic acidHCID 20147886—

Reaction Steps

A solution of tetraethyl (1-phenoxypropylidene)-bisphosphonate (2.1 g) in trimethyl bromosilane (8 ml) was kept at room temperature overnight, followed by evaporation in vacuo. The residue was stirred overnight in absolute ethanol. Evaporation in vacuo gave the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04732998
Source datasetuspto-grants-1988_03
ORD IDord-ce4bfa27ba54486e83aac61cf44faeef
Source noteuspto-grants-1988_03