Ammonium Hydroxide → L-Malic Acid

HRID 569722Notes

Reaction equation

HRID 569722 reaction equation
C(O)(=O)/C=C/C(O)=O.[NH4+].[OH-].C([O-])(=O)/C=C/C([O-])=O.[C:19]([O-:27])(=[O:26])[C@H:20]([CH2:22][C:23]([O-:25])=[O:24])[OH:21]>>[C:19]([O-:27])(=[O:26])[C@H:20]([CH2:22][C:23]([O-:25])=[O:24])[OH:21].[C:19]([OH:27])(=[O:26])[C@H:20]([CH2:22][C:23]([OH:25])=[O:24])[OH:21]

Participants

6

Reactant 4

HCID 14923Ammonium HydroxideHCID 444972Fumaric AcidHCID 5459792HCID 5459792, compound2×HCID 5460307Fumarate2×

Product 2

HCID 222656L-Malic AcidHCID 5459792HCID 5459792, compound

Procedure

If, for example, 300 g of fumaric acid per liter is introduced and the pH of the suspension with NH4OH is set at 8, a part of the undissolved NH4 fumarate is present as feedstock. With progressing conversion of the dissolved fumarate to L-malate, the fumarate that first was undissolved goes into solution and becomes accessible for conversion to L-malate. At harvest time, an L-malate concentration of about 300 g/l (calculated at L-malic acid) is obtained.

Sources & evidence

ORD record
ord-005a5a97b9af4985a0a6555b491305cc
Source dataset
uspto-grants-1988_03
Patent number
US04734368

Reaction notes

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