Sodium Hydroxide → L-Malic Acid

HRID 569723Notes

Reaction equation

HRID 569723 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[NH4+].[OH-:10].[OH-].[Na+]>>[C:1]([OH:8])(=[O:7])[C@H:2]([CH2:3][C:4]([OH:6])=[O:5])[OH:10]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 14923Ammonium HydroxideHCID 444972Fumaric Acid

Product 1

HCID 222656L-Malic Acid

Procedure

Cell mass grown according to example F is suspended in 16 liters of a 240 g/l solution containing fumaric acid (neutralized with NH4OH and NaOH in the molar ratio of 2 to 1). After 24 hours of incubation, 235 g of L-malic acid per liter of fermentation liquid is produced.

Sources & evidence

ORD record
ord-a31baba06ca74f89974d52e042d0d3b8
Source dataset
uspto-grants-1988_03
Patent number
US04734368

Reaction notes

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