HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 5-(2,1-Benzisothiazol-6-yl)-2,4-imidazolidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | 2,1-Benzisothiazole-6-carboxaldehyde | HCID 20146260 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-(2,1-Benzisothiazol-6-yl)-2,4-imidazolidinedione | HCID 20146261 | — |
Reaction Steps
18.6 g (0.114 mole) of 10c are stirred analogously to Example 1c in ethanol, methanol and water with 8.4 g (0.171 mole) of sodium cyanide and 43.8 g (0.456 mole) of ammonium carbonate at 60° C. for 16 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04734407 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-23669f41ba574c43847900f1d46071d8 |
| Source note | uspto-grants-1988_03 |