HCID 22837343, compound → HCID 22837345, compound

Participants

Reaction Steps

According to a similar procedure to that described in Example 1(l), t-butyl α-[3(S*)-amino-6(R*)-(p-fluorophenyl)-2-oxoperhydroazepin-1-yl]acetate [prepared as described in Example 6(e)] was reacted with butyl 4-phenyl-2(R)-trifluoromethanesulfonyloxybutyrate, to give a crude product, which was subjected to column chromatography through silica gel using a 3:1 by volume mixture of cyclohexane and ethyl acetate as eluent.

Provenance & Evidence