Hydrazine hydrate (1:1) → HCID 14099426, compound

HRID 569766Notes

Reaction equation

HRID 569766 reaction equation
[OH:1][CH2:2][C:3]1[N:4]=[CH:5][N:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=O)[CH2:15][CH2:16][C:17]([OH:19])=O)=[CH:10][CH:9]=2)[CH:7]=1.O.[NH2:22][NH2:23]>>[OH:1][CH2:2][C:3]1[N:4]=[CH:5][N:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3[CH2:15][CH2:16][C:17](=[O:19])[NH:22][N:23]=3)=[CH:10][CH:9]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20146318HCID 20146318, compound

Product 1

HCID 14099426HCID 14099426, compound

Procedure

Similarly, the reaction of 4-(4-hydroxymethyl-1H-imidazol-1-yl)-γ-oxobenzenebutanoic acid with hydrazine hydrate according to the procedure of this Example gives 4,5-dihydro-6-[4-(4-hydroxymethyl-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone (3g), mp 213.5°-215° C.

Sources & evidence

ORD record
ord-a4e3f6309d82489fbdb922d8e1ea0b53
Source dataset
uspto-grants-1988_03
Patent number
US04734415

Reaction notes

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