Hydrazine hydrate (1:1) → HCID 20146338, compound

HRID 569767Notes

Reaction equation

[CH2:1]([C:3]1[N:4]=[CH:5][N:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16](=O)[CH2:17][CH2:18][C:19]([OH:21])=O)=[CH:12][CH:11]=2)[C:7]=1[CH2:8][CH3:9])[CH3:2].O.[NH2:24][NH2:25]>>[CH2:1]([C:3]1[N:4]=[CH:5][N:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH2:17][CH2:18][C:19](=[O:21])[NH:24][N:25]=3)=[CH:12][CH:11]=2)[C:7]=1[CH2:8][CH3:9])[CH3:2]

Participants

Reactant 2

HCID 24654Hydrazine hydrate (1:1)

HCID 20146352HCID 20146352, compound

Product 1

HCID 20146338HCID 20146338, compound

Procedure

Similarly, the reaction of 4-(4,5-diethyl-1H-imidazol-1-yl)-γ-oxobenzenebutanoic acid with hydrazine hydrate according to the procedure of this Example gives 4,5-dihydro-6-[4-(4,5-diethyl-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone (3h).

Sources & evidence

ORD record: ord-892755a38313452883c57eb7d97eee20
Source dataset: uspto-grants-1988_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04734415

Reaction notes

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