Hydrazine hydrate (1:1) → HCID 14099427, compound

HRID 569768Notes

Reaction equation

HRID 569768 reaction equation
[N:1]1([C:10]2[CH:15]=[CH:14][C:13]([C:16](=O)[CH2:17][CH2:18][C:19]([OH:21])=O)=[CH:12][CH:11]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.O.[NH2:24][NH2:25]>>[N:1]1([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH2:17][CH2:18][C:19](=[O:21])[NH:24][N:25]=3)=[CH:12][CH:11]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20146344HCID 20146344, compound

Product 1

HCID 14099427HCID 14099427, compound

Procedure

Similarly, the reaction of 4-(1H-benzimidazol-1-yl)-γ-oxobenzenebutanoic acid with hydrazine hydrate according to the procedure of this Example gives 4,5-dihydro-6-[4-(1H-benzimidazol-1-yl)phenyl]-3(2H)-pyridazinone (3i), mp 262°-264° C.

Sources & evidence

ORD record
ord-0cb9da64d7b640229011c7f551eefc08
Source dataset
uspto-grants-1988_03
Patent number
US04734415

Reaction notes

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