HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 569770Generated: October 29, 2026
1,2-Hydrazinedicarboxaldehyde → 4,5-dihydro-6-[4-(4H-1,2,4-triazol-4-yl)phenyl]-3(2H)-pyridazinone
https://huagongshe.com/reaction/569770
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,2-Hydrazinedicarboxaldehyde | HCID 12342 | — |
| Reactant | 6-(4-aminophenyl)-2H-pyridazin-3-one | HCID 10867082 | — |
| Product | 4,5-dihydro-6-[4-(4H-1,2,4-triazol-4-yl)phenyl]-3(2H)-pyridazinone | HCID 14099434 | — |
Reaction Steps
A mixture of 6-(4-aminophenyl)-3(2H)-pyridazinone (3.78 g, 0.02 mol) and diformylhydrazine (1.76, 0.02 mol) are heated together at 220° C. for six hours. The solid mass is chromatographed and finally crystallized from acetonitrile/methanol to yield the product 4,5-dihydro-6-[4-(4H-1,2,4-triazol-4-yl)phenyl]-3(2H)-pyridazinone, mp 292.5°-293° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04734415 |
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| Source dataset | uspto-grants-1988_03 |
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| ORD ID | ord-509a0f39318f432cbae08f72e11612d3 |
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| Source note | uspto-grants-1988_03 |
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