Ethylenediamine → HCID 13887374, compound

HRID 569781Notes

Reaction equation

HRID 569781 reaction equation
[O:1]=[C:2]1[NH:7][N:6]=[C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=S)[NH2:15])=[CH:10][CH:9]=2)[CH:4]=[CH:3]1.[CH2:17](N)[CH2:18][NH2:19]>>[NH:19]1[CH2:18][CH2:17][N:15]=[C:14]1[C:11]1[CH:12]=[CH:13][C:8]([C:5]2[CH2:4][CH2:3][C:2](=[O:1])[NH:7][N:6]=2)=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 20146325HCID 20146325, compound

Product 1

HCID 13887374HCID 13887374, compound

Procedure

A slurry of 3 g of 4-(1,6-dihydro-6-oxo-3-pyridazinyl)benzenecarbothioamide in 5 ml of ethylenediamine is heated at 100° C. for 30 minutes when a clear solution is obtained. The solution is poured into 50 ml of ice-water and the solid is filtered, washed with a small volume of ice-water, and air-dried to give 2.5 g of the product, 6-[4-(4,5-dihydro-1H-imidazol-2-yl) phenyl]-4,5-dihydro-3(2H)-pyridazinone, mp 296°-297° dec.

Workup

  1. customis obtained
  2. filtrationthe solid is filtered
  3. washwashed with a small volume of ice-water
  4. customair-dried

Sources & evidence

ORD record
ord-74f96ea3b80c4e17a37d087bd993c12f
Source dataset
uspto-grants-1988_03
Patent number
US04734415

Reaction notes

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