Ethylenediamine → HCID 13887374, compound

Participants

Reaction Steps

A slurry of 3 g of 4-(1,6-dihydro-6-oxo-3-pyridazinyl)benzenecarbothioamide in 5 ml of ethylenediamine is heated at 100° C. for 30 minutes when a clear solution is obtained. The solution is poured into 50 ml of ice-water and the solid is filtered, washed with a small volume of ice-water, and air-dried to give 2.5 g of the product, 6-[4-(4,5-dihydro-1H-imidazol-2-yl) phenyl]-4,5-dihydro-3(2H)-pyridazinone, mp 296°-297° dec.

Provenance & Evidence