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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56981Generated: October 27, 2026

2-[5-Chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid → HCID 178460013, compound

https://huagongshe.com/reaction/56981

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[5-Chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acidHCID 117622549—
ReactantHCID 178507445HCID 178507445—
ProductHCID 178460013HCID 178460013—

Reaction Steps

126 mg (purity 66%, 0.25 mmol) of 2-[5-chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) (Example 12.1D) and 64 mg (0.27 mmol) of 4-[3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl]aniline (Example 1.1C) were reacted according to General Method 1. Yield: 76 mg (57% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434690B2
Source datasetuspto-grants-2016_09
ORD IDord-cb6e972d98da4960bec613ae6b35a17f
Source noteuspto-grants-2016_09