Acetic Acid → HCID 13784147, compound

Participants

Reaction Steps

To a mixed solvent of 30 ml of acetic acid and 10 ml of ethanol, 0.6 g (2.18 mmol, Referential Example 52) of 5-ethyl-2-(4-benzylpiperazino)-6-oxo-6,7,8,9-tetrahydro(5H)pyrimido[5,4-b]azepine and 0.06 g of 10% Pd-C were added. While causing hydrogen gas to flow through the reaction mixture, the reaction was allowed to proceed at 100° C. for 4 hours. Thereafter, the Pd/C was filtered off and the filtrate was dried to obtain 0.5 g of a light yellowish oily substance (yield: about 100%).

Provenance & Evidence