HCID 13784145, compound → HCID 13784148, compound

Participants

Reaction Steps

Added to 20 ml of ethanol were 0.1 g (0.3 mmol, Referential Example 51) of 2-(4-benzylpiperazino)-6-oxo-6,7,8,9-tetrahydro(5H)pyrimido[5,4-b]azepine and 0.01 g of 10% Pd-C. In a hydrogen atmosphere, they were reacted at 50° C. for 4 hours. After filtering off the Pd-C, the filtrate was dried to solid to obtain 0.074 g of colorless crystals in a quantitative yield.

Provenance & Evidence