Acetic Anhydride → HCID 13784168, compound

Participants

Reaction Steps

In acetic anhydride, 1.00 g of ethyl 4-amino-2-(4-benzylpiperazino)pyrimidine-5-carboxylate (the compound synthesized in Referential Example 60) was refluxed for 1 hour. After allowing the reaction mixture to cool down, acetic anhydride was distilled off and the resulting viscous oil was purified by silica gel column chromatography to obtain 0.68 g of the above-identified compound (yield: 61%).

Provenance & Evidence