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HRID57008

反应详情

EQUATION

反应方程式

HRID 57008 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：COc1cn(C(C[C@@H](C)OC)C(=O)Nc2ccc(C(=O)OC(C)(C)C)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N
HCID118877914

未命名化合物

PRODUCTS

生成物

1
结构：COc1cn(C(C[C@@H](C)OC)C(=O)Nc2ccc(C(=O)O)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N
HCID118877889

未命名化合物

PROCEDURE

实验过程

26 mg (0.05 mmol) of tert-butyl 4-({(4R)-2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methoxypentanoyl}amino)benzoate (enantiomerically pure diastereomer 1) were hydrolysed with TFA according to General Method 2. Yield: 11 mg (45% of theory)