Propargylamine → HCID 86673152, compound

HRID 570476Notes

Reaction equation

HRID 570476 reaction equation
N[CH2:2][CH2:3][NH:4][C:5]([C:7]1[S:8][CH:9]=[CH:10][C:11]=1[NH:12][C:13]1[CH:18]=[CH:17][N:16]=[C:15]2[NH:19][CH:20]=[CH:21][C:14]=12)=[O:6].[CH2:22](N)C#C>>[CH2:3]([NH:4][C:5]([C:7]1[S:8][CH:9]=[CH:10][C:11]=1[NH:12][C:13]1[CH:18]=[CH:17][N:16]=[C:15]2[NH:19][CH:20]=[CH:21][C:14]=12)=[O:6])[C:2]#[CH:22]

Participants

3

Reactant 2

HCID 239041PropargylamineHCID 509244533-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid (2-amino-ethyl)-amide

Product 1

HCID 86673152HCID 86673152, compound

Procedure

This compound was prepared in an analogous manner as 3-(1H-Pyrrolo[2,3-b]pyridin-4-ylamino)-thiophene-2-carboxylic acid (2-amino-ethyl)-amide using propargylamine instead of tert-butyl-2-amino ethyl carbamate to afford N-(prop-2-yn-1-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylamino)thiophene-2-carboxamide.

Sources & evidence

ORD record
ord-8ca7babbca7042a68fd6711ea1d2d11d
Source dataset
uspto-grants-2015_05
Patent number
US09023847B2

Reaction notes

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