反应详情

温度

80 °C

520 mg (4.331 mmol) of 1H-pyrazolo[3,4-d]pyrimidine and 1.461 g (6.496 mmol) of N-iodosuccinimide were dissolved in 10 ml of DMF and the mixture was heated at 80° C. for 3 h. After cooling, the mixture was concentrated on a rotary evaporator and the residue was stirred with dichloromethane, filtered off with suction and dried under high vacuum. 569 mg (53% of theory) of the target compound were obtained.

1. temperatureAfter cooling
2. concentrationthe mixture was concentrated on a rotary evaporator
3. filtrationfiltered off with suction
4. customdried under high vacuum
5. custom569 mg (53% of theory) of the target compound were obtained