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HRID57072

反应详情

EQUATION

反应方程式

HRID 57072 的结构方程式

REACTANTS

反应物

2
结构：Cc1nnc(-c2ccc(N)cc2)o1
HCID19542244

4-(5-Methyl-1,3,4-oxadiazol-2-yl)aniline

C9H9N3O

结构：CCC(C(=O)O)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O
HCID117622569

未命名化合物

PRODUCTS

生成物

1
结构：CCC(C(=O)Nc1ccc(-c2nnc(C)o2)cc1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O
HCID117622798

未命名化合物

PROCEDURE

实验过程

100 mg (0.29 mmol) of 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]butanoic acid (racemate) and 76 mg (0.43 mmol, 1.5 eq.) of 4-(5-methyl-1,3,4-oxadiazol-2-yl)aniline were reacted according to General Method 7. The crude product was purified by normal phase chromatography (mobile phase: dichloromethane/methanol 1-10% mixtures). Yield: 144 mg (99% of theory)

WORKUP

后处理

  1. customThe crude product was purified by normal phase chromatography (mobile phase: dichloromethane/methanol 1-10% mixtures)