HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Methyl-1,3,4-oxadiazol-2-yl)aniline → HCID 117622798, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Methyl-1,3,4-oxadiazol-2-yl)aniline | HCID 19542244 | — |
| Reactant | 2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]butanoic acid | HCID 117622569 | — |
| Product | HCID 117622798 | HCID 117622798 | — |
Reaction Steps
100 mg (0.29 mmol) of 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]butanoic acid (racemate) and 76 mg (0.43 mmol, 1.5 eq.) of 4-(5-methyl-1,3,4-oxadiazol-2-yl)aniline were reacted according to General Method 7. The crude product was purified by normal phase chromatography (mobile phase: dichloromethane/methanol 1-10% mixtures). Yield: 144 mg (99% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-99d76f873d664f14bdb991633c00fea4 |
| Source note | uspto-grants-2016_09 |