HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl cyanoacetate → HCID 367060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl cyanoacetate | HCID 7764 | — |
| Reactant | 3-Fluorobenzaldehyde | HCID 68009 | — |
| Catalyst | Pyrrolidine | HCID 31268 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 367060 | HCID 367060 | 98.5% |
Reaction Steps
A solution of cyanoacetic acid ethyl ester (1.1 g), 3-fluorobenzaldehyde (1.5 g) and pyrrolidine (0.043 g) in ethanol (10 mL) was stirred at room temperature for 2 hours. The precipitated solid was collected by filtration, and this obtained solid was washed with ethanol (40 mL) to give the title compound (2.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09023882B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-55f9db3ceccb48269777f29020aab8d2 |
| Source note | uspto-grants-2015_05 |