Hydrogen iodide → HCID 178481972, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of crude 3-methyl-4-oxo-N-(2-oxo-2-(thiophen-2-yl)ethyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboximidamide hydroiodide (40 mg) in 3N HCl (3 mL) was heated at 80° C. overnight. After being cooled to room temperature, the mixture was left at 4° C. for 2 hours and the precipitate was filtered and washed successively with cold water, ethyl acetate and diethyl ether to give the a mixture of the hydrochloride and hydroiodide salts of the title compound (24 mg).

Provenance & Evidence