Dicyclohexylcarbodiimide → N,N'-Dicyclohexylurea

Participants

Reaction Steps

Weighed into a 10 ml round-bottomed flask were 593 mg (2.4 mmol) of trifluoroacetamidomethyl benzoic acid. This acid was dissolved in 4 ml of anhydrous tetrahydrofuran and 324.4 mg (1.2 mmol) of 1,3-dicyclohexylcarbodiimide were added. It was left stirring, at ambient temperature, for 2 hours. The white precipitate of dicyclohexylurea obtained was filtered over a frit.

Provenance & Evidence