HCID 86705340, compound → HCID 86705341, compound

HRID 571136Notes

Reaction equation

HRID 571136 reaction equation
C([O:5][C:6]([C:8]1[S:9][C:10]([CH2:13][C:14]([C:19]([O:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[O:20])([CH2:17][CH3:18])[CH2:15][CH3:16])=[CH:11][CH:12]=1)=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[CH2:22]([O:21][C:19]([C:14]([CH2:17][CH3:18])([CH2:15][CH3:16])[CH2:13][C:10]1[S:9][C:8]([C:6]([OH:7])=[O:5])=[CH:12][CH:11]=1)=[O:20])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 1

HCID 86705340HCID 86705340, compound

Product 1

HCID 86705341HCID 86705341, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

To 5-(2-Benzyloxycarbonyl-2-ethyl-butyl)thiophene-2-carboxylic acid tert-butyl ester (24.9 g, 61.9 mmol) was added trifluoroacetic acid (20 mL), and the mixture was stirred at room temperature for 2 hours. The solvent was evaporated to give the title compound (quantitative)

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-c4f1645b4e3743d280e694ee72477b84
Source dataset
uspto-grants-2015_05
Patent number
US09024044B2

Reaction notes

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