Hydrochloric Acid → HCID 86681654, compound

Participants

Reaction Steps

To a solution of methyl 2-(5-(methylsulfonamido)-2-oxoindolin-1-yl)acetate (0.133 g, 0.446 mmol) in dioxane (5 ml), 12M HCl (4 ml, 48.0 mmol) was added, and the mixture was stirred at room temperature for 24 hours. The volatiles fractions were evaporated and the residue was dried under vacuum. Crude of 2-(5-(methylsulfonamido)-2-oxoindolin-1-yl)acetic acid (0.130 g, 0.446 mmol, 100% yield) was used for the next step without any further purification. MS/ESI+ 284.9 [MH]+.

Provenance & Evidence