HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-Dichloro-pyrimidin-4-ylamine → 5-Chloro-6-{4-[4-(4-fluoro-3-methyl-phenyl)-1-(1-methyl-azetidin-3-ylmethyl)-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-Dichloro-pyrimidin-4-ylamine | HCID 24219262 | — |
| Reactant | 4-[4-(4-fluoro-3-methyl-phenyl)-1-(1-methyl-azetidin-3-ylmethyl)-1H-imidazol-2-yl]-piperidine | HCID 118290304 | — |
| Product | 5-Chloro-6-{4-[4-(4-fluoro-3-methyl-phenyl)-1-(1-methyl-azetidin-3-ylmethyl)-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine | HCID 118290319 | — |
Reaction Steps
The title compound was prepared according to the procedure described for the preparation of compound “1” by using 4-[4-(4-fluoro-3-methyl-phenyl)-1-(1-methyl-azetidin-3-ylmethyl)-1H-imidazol-2-yl]-piperidine and 5,6-Dichloro-pyrimidin-4-ylamine. LC-MS (M+H=471, obsd=471).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434714B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-1f7b049279784fdfbeffea1fc1f551b1 |
| Source note | uspto-grants-2016_09 |