HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(2-methoxy-1-phenylethyl)urea → HCID 178495747, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(2-methoxy-1-phenylethyl)urea | HCID 89524417 | — |
| Reactant | HCID 178506289 | HCID 178506289 | — |
| Product | HCID 178495747 | HCID 178495747 | — |
Reaction Steps
In a manner similar to that described in Example 30 (Step 1), 6-chloro-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine was reacted with (S)-1-(2-methoxy-1-phenylethyl)urea (BrettPhos precatalyst, KOtBu, dioxane, 90° C., overnight) to provide 1-[(1S)-2-methoxy-1-phenylethyl]-3-[3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]urea. MS ESI calc'd. for C17H16F3N5O2[M+1]+ 380, found 380.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09023865B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-73c0c8779c7d441cae456bba98c61c69 |
| Source note | uspto-grants-2015_05 |