(4-(2-Hydroxyethoxy)phenyl)(4-methoxyphenyl)methanone → 1-(4-(2-Hydroxyethoxy)phenyl)-1-(4-methoxyphenyl)prop-2-yn-1-ol

Participants

Reaction Steps

The procedure of Step 1 of Example 5 of U.S. Pat. No. 7,465,415B2 was followed except that the product of Step 5 above was used in place of (4-fluorophenyl)(4-(2-hydroxyethoxy)phenyl)methanone to produce 1-(4-(2-hydroxyethoxy)phenyl)-1-(4-methoxyphenyl)prop-2-yn-1-ol. The product was used without further purification.

Provenance & Evidence