Propanethioamide → HCID 86697863, compound

HRID 571627Notes

Reaction equation

HRID 571627 reaction equation
Br.[Br:2][CH:3]1[CH2:9][CH2:8][NH:7][CH2:6][CH2:5][C:4]1=O.[C:11]([NH2:15])(=[S:14])[CH2:12][CH3:13]>C(O)C>[BrH:2].[CH2:12]([C:11]1[S:14][C:3]2[CH2:9][CH2:8][NH:7][CH2:6][CH2:5][C:4]=2[N:15]=1)[CH3:13]

Participants

4

Reactant 2

HCID 2760628PropanethioamideHCID 226207665-Bromoazepan-4-one hydrobromide

Product 1

HCID 86697863HCID 86697863, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

0.40 g (1.47 mmol) 5-bromo-azepan-4-one hydrobromide, 0.13 g (1.47 mmol) thiopropionamide and 3 mL ethanol were stirred under reflux for 3 hours. The reaction was allowed to cool to RT and was filtered. The filtrate was concentrated to dryness and dried.

Workup

  1. temperatureunder reflux for 3 hours
  2. filtrationwas filtered
  3. concentrationThe filtrate was concentrated to dryness
  4. customdried

Sources & evidence

ORD record
ord-c956829b3f564bf7ae02c6c68cda58b7
Source dataset
uspto-grants-2015_05
Patent number
US09029360B2

Reaction notes

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