反应详情

A solution of 2-(benzyloxy)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (0.02 g, 0.087 mmol) in a DCM (1 mL) was treated with bromoacetyl bromide (7.6 μL, 17.6 mg, 0.087 mmol) at 0° C. The solvents were evaporated in vacuo to yield 1-(2-benzyloxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-2-bromo-ethanone as a white solid, that was used in the next step without further purification.

1. customThe solvents were evaporated in vacuo