HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 86659418, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86659418 | HCID 86659418 | — |
Reaction Steps
To a suspension of compound AE or AM′ (1.0 equiv.) in DMF, DIC (1.5 equiv.) or EDCI (1.5 equiv.), HOBt (1.5 equiv.) and the selected amine (1.5-5.0 equiv.) were added. The mixture was stirred at R.T. for 12-72 Hrs or heated through microwave irradiation for 5 min at 150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029393B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-65e6d132dce74b45a46e9893fbfe10ce |
| Source note | uspto-grants-2015_05 |