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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 572458Generated: November 3, 2026

Indole-5-carbonitrile → Indole

https://huagongshe.com/reaction/572458

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-5-carbonitrileHCID 27513—
Reactant1H-indole-2-carbonitrileHCID 3787599—
ProductIndoleHCID 798—

Reaction Steps

The A ring indole of compounds 31 and 32 was synthesized using the same approach as 8f described in Scheme 3 above from 1H-indole-5-carbonitrile or 1H-indole-2-carbonitrile as starting material. Crude product was purified by column chromatography. Description of synthesis of compounds 31 and 32 is provided below in Example 11.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09029408B2
Source datasetuspto-grants-2015_05
ORD IDord-dc5102d6152b4e4eb62f317ab86e575b
Source noteuspto-grants-2015_05