反应详情

The A ring indole of compounds 31 and 32 was synthesized using the same approach as 8f described in Scheme 3 above from 1H-indole-5-carbonitrile or 1H-indole-2-carbonitrile as starting material. Crude product was purified by column chromatography. Description of synthesis of compounds 31 and 32 is provided below in Example 11.

1. customCrude product was purified by column chromatography
2. customDescription of synthesis of compounds 31
3. custom32 is provided below in Example 11