Tetrabutylammonium Fluoride → HCID 86719094, compound

Participants

Reaction Steps

To the stirred solution of methyl 2-(5-((tert-butyldimethylsilyl)oxy)pyridin-2-yl)acetate (1 g, 3.5 mmol) in THF was added TBAF (1M, 3.5 ml) at room temperature. The whole mixture was stirred at room temperature overnight. It was evaporated and extracted with EtOAc, the organic layer was washed with water, evaporated and purified by a standard method.

Provenance & Evidence