Sodium Methoxide → HCID 90150897, compound

Participants

Reaction Steps

A solution of methyl 2-(2-bromothiazol-4-yl)acetate (80 mg, 0.34 mmol), and sodium methanolate (300 mg) in MeOH was stirred at 85° C. overnight. Then the reaction mixture was concentrated to give the desired product. 1H NMR (METHANOL-d4) δ: 4.04 (s, 3H), 3.47 (d, J=1.1 Hz, 2H), 3.37 (s, 1H). LC-MS: m/z (M+H)=174.2

Provenance & Evidence