1-Methylpiperazine → HCID 178434641, compound

HRID 57300Notes

Reaction equation

HRID 57300 reaction equation
Br[CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[N:7]=[C:8]([C:10]3[C:14]([CH3:15])=[N:13][NH:12][C:11]=3[NH2:16])[S:9][C:5]=2[CH:4]=1.[CH3:19][N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:15][C:14]1[C:10]([C:8]2[S:9][C:5]3[CH:4]=[C:3]([CH2:2][N:23]4[CH2:24][CH2:25][N:20]([CH3:19])[CH2:21][CH2:22]4)[CH:18]=[CH:17][C:6]=3[N:7]=2)=[C:11]([NH2:16])[NH:12][N:13]=1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 178434639HCID 178434639, compound

Product 1

HCID 178434641HCID 178434641, compound

Procedure

The title compound (9 mg) was prepared starting from 20 mg of 4-(6-bromomethylbenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine and excess 1-methylpiperazine. MS (m/z, ES+): 343.1 (M+1, 20%), 244.1 (M−CH3N(CH2)4N+1, 100%).

Sources & evidence

ORD record
ord-17d9454ee2724b6980d4ad3539850f59
Source dataset
uspto-grants-2016_09
Patent number
US09434720B2

Reaction notes

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