反应详情

A solution of EXAMPLE 339F (484 mg) in dichloromethane (22 mL) was cooled in an ice bath and 2,2,2-trifluoroacetic acid (11 mL) was added. The reaction was stirred for 2 hours, concentrated and the crude product was chromatographed on silica gel with 7N-methanolic ammonia in methylene chloride.

1. concentrationconcentrated
2. customthe crude product was chromatographed on silica gel with 7N-methanolic ammonia in methylene chloride