HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-1-ethyl-1H-pyrazolo[4,3-d]pyrimidine → HCID 66727973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-1-ethyl-1H-pyrazolo[4,3-d]pyrimidine | HCID 71445808 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 66727973 | HCID 66727973 | 93.9% |
Reaction Steps
A mixture of 7-chloro-1-ethyl-1H-pyrazolo[4,3-d]pyrimidine (105 mg), TEA (0.088 mL) and 10% Pd—C (30 mg) in AcOEt (5 mL) was hydrogenated under balloon pressure at room temperature for 2 h. The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to give the title compound (80 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09029536B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-82466f85a4994758adcb1ded58cd0c9f |
| Source note | uspto-grants-2015_05 |