HRID573834

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID89373168

未命名化合物

结构：CC(C(=O)N=[N+]=[N-])C(C)c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1.CC(N=C=O)C(C)c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1

HCID90406195

未命名化合物

PRODUCTS

生成物

$结构：Cc1ccc(C(C)C)c(N2C(=O)CS/C2=N\C(=O)NC(C)C(C)c2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1$

HCID90404241

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as described in Example 35 using 1-(2-isopropyl-5-methylphenyl)thiourea and 2-methyl-3-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)butanoyl azide/3-(4-(3-isocyanatobutan-2-yl)phenyl)-1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazole (C35a) and isolated as an off-white powder (0.146 g, 39%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-59c1829f9dd34c3ba4e6af68e031de5c
来源数据集: uspto-grants-2015_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09029560B2
来源说明: uspto-grants-2015_05

反应 SMILES

[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:5]=1[NH:11][C:12]([NH2:14])=[S:13])([CH3:3])[CH3:2].C[CH:16](C(C1C=CC(C2N=CN(C3C=CC(OC(F)(F)F)=CC=3)N=2)=CC=1)C)[C:17](N=[N+]=[N-])=[O:18].[N:46]([CH:49]([CH3:74])[CH:50]([C:52]1[CH:57]=[CH:56][C:55]([C:58]2[N:62]=[CH:61][N:60]([C:63]3[CH:68]=[CH:67][C:66]([O:69][C:70]([F:73])([F:72])[F:71])=[CH:65][CH:64]=3)[N:59]=2)=[CH:54][CH:53]=1)[CH3:51])=[C:47]=[O:48]>>[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:5]=1[N:11]1[C:17](=[O:18])[CH2:16][S:13]/[C:12]/1=[N:14]\[C:47]([NH:46][CH:49]([CH:50]([C:52]1[CH:57]=[CH:56][C:55]([C:58]2[N:62]=[CH:61][N:60]([C:63]3[CH:68]=[CH:67][C:66]([O:69][C:70]([F:72])([F:71])[F:73])=[CH:65][CH:64]=3)[N:59]=2)=[CH:54][CH:53]=1)[CH3:51])[CH3:74])=[O:48])([CH3:3])[CH3:2]