反应详情

温度

40 °C

Under an argon atmosphere, 2,4-bis(docosyloxy)benzaldehyde (2.99 g, 3.96 mmol) was dissolved in a mixed solvent of dehydrating tetrahydrofuran (60 mL) and methanol (6.0 mL), sodium borohydride (375 mg, 9.91 mmol) was added, and the mixture was stirred at 40° C. for 2 hr. After completion of the reaction, purified water (2.0 mL) was added dropwise to decompose unreacted sodium borohydride and the mixture was filtered through celite. The filtrate was concentrated under reduced pressure, methanol was added, and the precipitated solid was collected by filtration. The obtained solid was dried under reduced pressure to give the title compound (2.77 g, 92.9%) as a white solid.

1. additionwas added
2. customAfter completion of the reaction
3. custompurified water (2.0 mL)
4. additionwas added dropwise
5. filtrationthe mixture was filtered through celite
6. concentrationThe filtrate was concentrated under reduced pressure, methanol
7. additionwas added
8. filtrationthe precipitated solid was collected by filtration
9. customThe obtained solid was dried under reduced pressure